AR-News: Stupid Mouse Experiments
Adam Weissman, Wetlands Preserve
adam at wetlands-preserve.org
Mon Jun 7 20:18:54 EDT 2004
WASHINGTON (Reuters) - Parents used to blame Grandpa for that
annoying cowlick that refused to be tamed by brush or lotion, but
scientists now say a single gene could be to blame.
Of course, Grandpa may have passed along the gene, called Frizzled6,
the researchers write in this week's issue of the Proceedings of the
National Academy of Sciences.
But it must be important, as it also affects the development of hair
whorls in mice and is found in creatures as primitive as fruit flies,
Jeremy Nathans and fellow geneticists at Johns Hopkins University in
Baltimore found.
It may even affect the brain, they said.
To study the gene's importance, Nathan's team bred genetically
engineered mice that lacked Frizzled6 entirely and also created mice
that had various active versions of the gene.
Mice that lacked the gene were normal and healthy but showed some
unusual hair patterns such as whorls of hair on their hind feet or
the back of their heads.
The researchers noted that a team reported in the journal Genetics
last year that they had found a link between hair whorls and whether
people are left- or right-handed.
This suggested "the possibility that the same system that patterns
hair may also play a role in left-right asymmetry in the brain," they
concluded.
Reuters
May 24 2004 7:09PM
--
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influence.
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